UniProt P08515
Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B (P08515)
Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B (UniProt P08515), EC 2.5.1.18, 2.7.11.22: 70 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 52 pockets.…
- UniProt
- P08515
- Protein
- Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans…
- EC
- 2.5.1.18, 2.7.11.22, 5.2.1.8
- Experimental structures
- 70
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 52 · 10 records with a druggable one
Structures
71 records of P08515 in the MolNFT archive: 70 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B8X | Glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription… | x-ray diffraction | A | — | — |
| 1B8X | Glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription… | x-ray diffraction | A | — | — |
| 1BG5 | Crystal structure of the ankyrin binding domain of alpha-NA,K-ATPase as a fusion protein with… | x-ray diffraction | A | — | — |
| 1BG5 | Crystal structure of the ankyrin binding domain of alpha-na, K-ATPase as a fusion protein with… | x-ray diffraction | A | — | — |
| 1DUG | Structure of the fibrinogen G chain integrin binding and factor xiiia crosslinking sites obtained… | x-ray diffraction | A, B | — | — |
| 1DUG | Structure of the fibrinogen G chain integrin binding and factor xiiia crosslinking sites obtained… | x-ray diffraction | A, B | — | — |
| 1GNE | The three-dimensional structure of glutathione S-transferase of schistosoma japonicum fused with a… | x-ray diffraction | A | — | — |
| 1GNE | The three-dimensional structure of glutathione S-transferase of schistosoma japonicum fused with a… | x-ray diffraction | A | — | — |
| 1GTA | Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from… | x-ray diffraction | A | — | — |
| 1GTA | Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from… | x-ray diffraction | A | — | — |
| 1GTB | Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from… | x-ray diffraction | A | — | — |
| 1GTB | Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from… | x-ray diffraction | A | — | — |
| 1M99 | Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1M99 | Crystal structure of the 26 kda glutathione S-transferase from schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1M9A | Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1M9A | Crystal structure of the 26 kda glutathione S-transferase from schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1M9B | Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1M9B | Crystal structure of the 26 kda glutathione S-transferase from schistosoma japonicum complexed with… | x-ray diffraction | A | — | — |
| 1U87 | Crystal Structure Of The 26 Kda Glutathione S-Transferase Y7F mutant From Schistosoma Japonicum… | x-ray diffraction | A | — | — |
| 1U87 | Crystal structure of the 26 kda glutathione S-transferase Y7F mutant from schistosoma japonicum… | x-ray diffraction | A | — | — |
| 1U88 | Crystal Structure Of The 26 Kda Glutathione S-Transferase Y7F mutant From Schistosoma Japonicum… | x-ray diffraction | A, B | — | — |
| 1U88 | Crystal structure of the 26 kda glutathione S-transferase Y7F mutant from schistosoma japonicum… | x-ray diffraction | A, B | — | — |
| 1UA5 | Non-fusion GST from S. japonicum in complex with glutathione | x-ray diffraction | A | — | — |
| 1UA5 | Non-fusion GST from S. japonicum in complex with glutathione | x-ray diffraction | A | — | — |
| 1Y6E | Orthorhombic glutathione S-transferase of Schistosoma japonicum | x-ray diffraction | A, B | — | — |
| 1Y6E | Orthorhombic glutathione S-transferase of schistosoma japonicum | x-ray diffraction | A, B | — | — |
| 3CRT | Structural characterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3CRT | Structural characterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3CRU | Structural characterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3CRU | Structural characterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3D0Z | Structural charcaterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3D0Z | Structural charcaterization of an engineered allosteric protein | x-ray diffraction | A | — | — |
| 3QMZ | Crystal structure of the cytoplasmic dynein heavy chain motor domain | x-ray diffraction | T, S | — | — |
| 3QMZ | Crystal structure of the cytoplasmic dynein heavy chain motor domain | x-ray diffraction | T, S | — | — |
| 4AI6 | Dynein Motor Domain - ADP complex | x-ray diffraction | A, B | — | — |
| 4AI6 | Dynein motor domain - ADP complex | x-ray diffraction | A, B | — | — |
| 4AKG | Dynein Motor Domain - ATP complex | x-ray diffraction | A, B | — | — |
| 4AKG | Dynein motor domain - ATP complex | x-ray diffraction | A, B | — | — |
| 4AKH | Dynein Motor Domain - AMPPNP complex | x-ray diffraction | A, B | — | — |
| 4AKH | Dynein motor domain - amppnp complex | x-ray diffraction | A, B | — | — |
| 4AKI | Dynein Motor Domain - LuAc derivative | x-ray diffraction | A, B | — | — |
| 4AKI | Dynein motor domain - luac derivative | x-ray diffraction | A, B | — | — |
| 4ECB | Chimeric GST Containing Inserts of Kininogen Peptides | x-ray diffraction | A, B | — | — |
| 4ECB | Chimeric GST containing inserts of kininogen peptides | x-ray diffraction | A, B | — | — |
| 4ECC | Chimeric GST Containing Inserts of Kininogen Peptides | x-ray diffraction | A | — | — |
| 4ECC | Chimeric GST containing inserts of kininogen peptides | x-ray diffraction | A | — | — |
| 4WR4 | Crystal Structure of GST Mutated with Halogenated Tyrosine (7bGST-1) | x-ray diffraction | A | — | — |
| 4WR4 | Crystal structure of GST mutated with halogenated tyrosine (7BGST-1) | x-ray diffraction | A | — | — |
| 4WR5 | Crystal Structure of GST Mutated with Halogenated Tyrosine (7cGST-1) | x-ray diffraction | A | — | — |
| 4WR5 | Crystal structure of GST mutated with halogenated tyrosine (7CGST-1) | x-ray diffraction | A | — | — |
| 5GZZ | Crystal Structure of FIN219-SjGST complex with JA | x-ray diffraction | B, C, D, E, F, G | GSH | — |
| 5GZZ | Crystal structure of FIN219-sjgst complex with ja | x-ray diffraction | B, C, D, E, F, G | — | — |
| 6JI6 | Crystal structure of glutathione S-transferase complexed and modified with glutathione | x-ray diffraction | A | GSH | — |
| 6N8U | DRAFT model of Schistosoma japonicum Glutathione S-transferase expression tag | x-ray diffraction | A, B | — | — |
| 6N8U | Draft model of schistosoma japonicum glutathione S-transferase expression tag | x-ray diffraction | A, B | — | — |
| 6RWD | Crystal structure of sjgst in complex with gsh and ellagic acid at 1.53 ångström resolution | x-ray diffraction | A, B | GSH, NA, CL, REF | — |
| 7AL7 | The crystal structure of human il-18 in complex with human il-18 binding protein | x-ray diffraction | B | — | — |
| 7ESG | Crystal structure of haloarcula marismortui cheb with glutathione S- transferase expression tag | x-ray diffraction | A | — | — |
| 7NT8 | Influenza virus H3N2 nucleoprotein - R416A mutant | x-ray diffraction | A, B | — | 9 (best 0.74) |
| 7NT8 | Influenza virus H3N2 nucleoprotein - R416A mutant | x-ray diffraction | A, B | — | — |
11 records more on the page itself.
Ligands
- GSH · Glutathione · in 3 records
- CL · Chloride ion · in 2 records
- SO4 · Sulfate ion · in 2 records
- 0IH · (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid · in 1 record
- 1QK · 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium · in 1 record
- NA · Sodium ion · in 1 record
- REF · 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione · in 1 record
Experiment against prediction
- 1UA5 chain A against the predicted model P08515: TM-score 1.00, RMSD 0.34 Å
- 1UA5 chain A against the predicted model P08515: TM-score 1.00, RMSD 0.34 Å
- 6JI6 chain A against the predicted model P08515: TM-score 1.00, RMSD 0.34 Å
- 1Y6E chain A against the predicted model P08515: TM-score 1.00, RMSD 0.38 Å
- 1Y6E chain A against the predicted model P08515: TM-score 1.00, RMSD 0.38 Å
- 1M99 chain A against the predicted model P08515: TM-score 0.99, RMSD 0.41 Å
- 1M99 chain A against the predicted model P08515: TM-score 0.99, RMSD 0.41 Å
- 3QMZ chain T against the predicted model P08515: TM-score 0.99, RMSD 0.40 Å
- 3QMZ chain T against the predicted model P08515: TM-score 0.99, RMSD 0.40 Å
- 4ECC chain A against the predicted model P08515: TM-score 0.99, RMSD 0.40 Å
Elsewhere
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