MolNFT v1 · #166971 · protein
Crystal structure of N-[(4-METHOXYPHENYL)SULFONYL]-N-(4-{[(4- METHOXYPHENYL)SULFONYL]AMINO}NAPHTHALEN-1-YL)GLYCINE bound to human KEAP1 kelch domain
6V6Z: “Crystal structure of N-[(4-METHOXYPHENYL)SULFONYL]-N-(4-{[(4…”. X-ray diffraction, 2 ligands (Q5Y, NA). MolNFT v1 #166971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6V6Z
- Type
- protein
- Length
- 1,141 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q14145
- Ligands
- Q5Y, NA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, D | — | protein | 285 | — | Q14145 |
| B | — | protein | 286 | — | Q14145 |
Ligands and binding sites
- Q5Y · N-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl) sulfonyl]amino}naphthalen-1-yl)glycine · ligand · 4 copies · chains A, B, C, D
- NA · Sodium ion · metal · 8 copies · chains A, B, C, D
- FMT · Formic acid · additive · 61 copies · chains A, C, B, D
- DTD · Dithiane diol · additive · chains C, D
- DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6V6Z · Crystal structure of N-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl)sulfonyl]amino}… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14145
- Elsewhere: RCSB PDB 6V6Z · PDBe 6V6Z · UniProt Q14145
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