MolNFT v1 · #166878 · protein
Human POLY(ADP-ribose) polymerase 12, catalytic fragment with four point mutations in complex with rbn-2397
6V3W: “Human POLY(ADP-ribose) polymerase 12, catalytic fragment with four point mutations in complex with rbn-2397”. X-ray diffraction, 2 ligands (QO4, CL). MolNFT v1 #166878 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6V3W
- Type
- protein
- Length
- 183 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9H0J9
- Ligands
- QO4, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 183 | — | Q9H0J9 |
Ligands and binding sites
- QO4 · 5-{[(2S)-1-(3-oxo-3-{4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl}propoxy)propan-2-yl]amino}-4-(trifluoromethyl)pyridazin-3(2H)-one · ligand · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6V3W · Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment with four point mutations in… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H0J9 · AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase PARP12 (Q9H0J9) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H0J9
- Elsewhere: RCSB PDB 6V3W · PDBe 6V3W · UniProt Q9H0J9
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