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MolNFT v1 · #166806 · protein

Crystal structure of the bromodomain of human BRD7 bound to BI7273

6V1E: “Crystal structure of the bromodomain of human BRD7 bound to BI7273”. X-ray diffraction, 1 ligand (5SW). MolNFT v1 #166806 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6V1E
Type
protein
Length
119 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9NPI1
Ligands
5SW

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein119—Q9NPI1

Ligands and binding sites

  • 5SW · 4-[4-[(dimethylamino)methyl]-3,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one · ligand · chains A
  • EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6V1E · Crystal structure of the bromodomain of human BRD7 bound to BI7273 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NPI1 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 7 (Q9NPI1) · a predicted model of the same protein · chain A against A, TM-score 0.99

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