MolNFT v1 · #166798 · protein
Crystal structure of the bromodomain of human BRD7 bound to TP472
6V16: “Crystal structure of the bromodomain of human BRD7 bound to TP472”. X-ray diffraction, 1 ligand (QMG). MolNFT v1 #166798 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6V16
- Type
- protein
- Length
- 227 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NPI1
- Ligands
- QMG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 118 | — | Q9NPI1 |
| B | — | protein | 109 | — | Q9NPI1 |
Ligands and binding sites
- QMG · 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains A
- HEZ · Hexane-1,6-diol · additive · chains B
- GOL · Glycerol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6V16 · Crystal structure of the bromodomain of human BRD7 bound to TP472 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NPI1 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 7 (Q9NPI1) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NPI1
- Elsewhere: RCSB PDB 6V16 · PDBe 6V16 · UniProt Q9NPI1
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