MolNFT v1 · #166587 · protein
Structure of human ATP citrate lyase E599Q mutant in complex with MG2+, citrate, ATP and CoA
6UUW: “Structure of human ATP citrate lyase E599Q mutant in complex with MG2+, citrate, ATP and CoA”. Electron microscopy, 4 ligands (ADP, COA, Y2A). MolNFT v1 #166587 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UUW
- Type
- protein
- Length
- 4,136 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P53396
- Ligands
- ADP, COA, Y2A, UNL
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 1034 | — | P53396 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 4 copies · chains A, B, C, D
- COA · Coenzyme A · ligand · 4 copies · chains A, C, B, D
- Y2A · (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy) ethyl]butanedioic acid · ligand · 4 copies · chains A, B, C, D
- UNL · Unknown ligand · ion · 2 copies
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UUW · Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and… · the same entry in another collection · chain D against D, TM-score 1.00
- P53396 · AlphaFold monomer V2.0 prediction for ATP-citrate synthase (P53396) · a predicted model of the same protein · chain D against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53396
- Elsewhere: RCSB PDB 6UUW · PDBe 6UUW · UniProt P53396
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.