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MolNFT v1 · #166396 · protein + DNA

Y271G DNA polymerase beta ternary complex with templating adenine and incoming R8-oxo-GTP

6UOM: “Y271G DNA polymerase beta ternary complex with templating adenine and incoming R8-oxo-GTP”. X-ray diffraction, 3 ligands (8GT, NA, MN). MolNFT v1 #166396 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6UOM
Type
protein + DNA
Length
357 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P06746
Ligands
8GT, NA, MN

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
T—dna16——
P—dna10——
D—dna5——
A—protein326—P06746

Ligands and binding sites

  • 8GT · 8-oxo-guanosine-5'-triphosphate · ligand · chains T, P, A
  • NA · Sodium ion · metal · 4 copies · chains P, A, D
  • MN · Manganese (II) ion · metal · 2 copies · chains A
  • EDO · 1,2-ethanediol · additive · 2 copies · chains T, D, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6UOM · Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP · the same entry in another collection · chain T against T, TM-score 1.00
  • P06746 · AlphaFold monomer V2.0 prediction for DNA polymerase beta (P06746) · a predicted model of the same protein · chain A against A, TM-score 0.95

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