MolNFT v1 · #166394 · protein + DNA

Y271G DNA polymerase beta substrate complex with templating cytosine and incoming R8-oxo-GTP

6UOK: “Y271G DNA polymerase beta substrate complex with templating cytosine and incoming R8-oxo-GTP”. X-ray diffraction, 5 ligands (8GT, NA, MN). MolNFT v1 #166394 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6UOK
Type: protein + DNA
Length: 710 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P06746
Ligands: 8GT, NA, MN, MG, CL

Structure

x-ray diffraction · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B, T	—	dna	16	—	—
C, P	—	dna	10	—	—
E, D	—	dna	5	—	—
F	—	protein	326	—	P06746
A	—	protein	322	—	P06746

Ligands and binding sites

8GT · 8-oxo-guanosine-5'-triphosphate · ligand · 2 copies · chains B, C, F, A, T, P
NA · Sodium ion · metal · 6 copies · chains E, F, C, A, D, P
MN · Manganese (II) ion · metal · 6 copies · chains F, A
MG · Magnesium ion · metal · chains D
CL · Chloride ion · ion · chains B
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6UOK · Y271G DNA polymerase beta substrate complex with templating cytosine and incoming… · the same entry in another collection · chain D against D, TM-score 1.00
P06746 · AlphaFold monomer V2.0 prediction for DNA polymerase beta (P06746) · a predicted model of the same protein · chain F against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06746
Elsewhere: RCSB PDB 6UOK · PDBe 6UOK · UniProt P06746

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.