MolNFT v1 · #166296 · protein
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
6ULN: “Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation”. X-ray diffraction, 2 ligands (MG, SO4). MolNFT v1 #166296 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ULN
- Type
- protein
- Length
- 810 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- C1K0Y1, P61769, P01111
- Ligands
- MG, SO4
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | C1K0Y1 |
| B | — | protein | 99 | — | P61769 |
| C | — | protein | 9 | — | P01111 |
| D | — | protein | 189 | — | — |
| E | — | protein | 240 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, E
- SO4 · Sulfate ion · ion · 2 copies · chains A, B, D, E
- GOL · Glycerol · additive · 6 copies · chains A, E, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6ULN · Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation · the same entry in another collection · chain B against B, TM-score 1.00
- P61769 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P61769) · a predicted model of the same protein · chain B against A, TM-score 0.99
- P01111 · AlphaFold monomer V2.0 prediction for GTPase NRAS (P01111) · a predicted model of the same protein · chain C against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C1K0Y1
- Every structure of UniProt P61769
- Every structure of UniProt P01111
- Elsewhere: RCSB PDB 6ULN · PDBe 6ULN · UniProt C1K0Y1 · UniProt P61769 · UniProt P01111
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.