MolNFT v1 · #166208 · protein

Artificial iron proteins: modelling the active sites in non-heme dioxygenases

6UIZ · Streptavidin: “Artificial iron proteins: modelling the active sites in non-heme dioxygenases”. X-ray diffraction, 1 ligand (QG4), 1 pocket (best druggability 0.50). MolNFT v1 #166208 on GenesisL1: 3D structure, binding sites and…

PDB: 6UIZ
Type: protein
Length: 124 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Streptavidin
UniProt: P22629
Ligands: QG4
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Streptavidin	protein	124	8% helix, 54% strand	P22629

Ligands and binding sites

QG4 · {N-(2-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(triaza-1,2-dien-2-ium-1-ide-kappaN~1~)iron(4+) · ligand · chains A
ACT · Acetate ion · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.50	0.81	19	QG4

Compared structures

6UIZ · Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22629
Elsewhere: RCSB PDB 6UIZ · PDBe 6UIZ · UniProt P22629

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.