MolNFT v1 · #166137 · protein
Crystal structure of the Fab fragment of anti-tnfa antibody infliximab (remicade) in a I-centered orthorhombic crystal form, lot C
6UGV: “Crystal structure of the Fab fragment of anti-tnfa antibody infliximab (remicade) in a I-centered…”. X-ray diffraction, 1 ligand (MRY). MolNFT v1 #166137 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UGV
- Type
- protein
- Length
- 868 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A8K008, Q6P5S8
- Ligands
- MRY
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H, A | — | protein | 221 | — | A8K008 |
| L, B | — | protein | 213 | — | Q6P5S8 |
Ligands and binding sites
- MRY · Meso-erythritol · ligand · 2 copies · chains H, A
- EDO · 1,2-ethanediol · additive · 3 copies · chains H, L, A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UGV · Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a… · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8K008
- Every structure of UniProt Q6P5S8
- Elsewhere: RCSB PDB 6UGV · PDBe 6UGV · UniProt A8K008 · UniProt Q6P5S8
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