Solution structure of the razul domain from 26S proteasome subunit HRPN10/S5A complexed with the azul domain from E3 ligase E6AP/UBE3A

Structure

solution nmr · 2 distinct chains · 45% helix, 0% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 832 Ų buried · 5 hydrogen bonds · protein-protein

Compared structures

• 6U19 · Solution Structure of the RAZUL domain from 26S proteasome subunit hRpn10/S5a complexed… · the same entry in another collection · chain A against A, TM-score 1.00
• Q05086 · AlphaFold monomer V2.0 prediction for ubiquitin-protein ligase E3A (Q05086) · a predicted model of the same protein · chain B against A, TM-score 0.86
• P55036 · AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 4… · a predicted model of the same protein · chain A against A, TM-score 0.50

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P55036
• Every structure of UniProt Q05086
• Elsewhere: RCSB PDB 6U19 · PDBe 6U19 · UniProt P55036 · UniProt Q05086