MolNFT v1 · #165485 · protein

HUMAN HPF1

6TX2 · Histone parylation factor 1: “HUMAN HPF1”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.34). MolNFT v1 #165485 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6TX2
Type: protein
Length: 304 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Histone parylation factor 1
UniProt: Q9NWY4
Ligands: NA
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histone parylation factor 1	protein	304	49% helix, 8% strand	Q9NWY4

Ligands and binding sites

NA · Sodium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.34	0.75	16	empty

Compared structures

6TX2 · Human HPF1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9NWY4 · AlphaFold monomer V2.0 prediction for histone parylation factor 1 (Q9NWY4) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NWY4
Elsewhere: RCSB PDB 6TX2 · PDBe 6TX2 · UniProt Q9NWY4

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