MolNFT v1 · #165407 · protein

Human aldose reductase in complex with ALR25

6TUC: “Human aldose reductase in complex with ALR25”. X-ray diffraction, 2 ligands (NXK, NAP). MolNFT v1 #165407 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6TUC
Type: protein
Length: 313 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P15121
Ligands: NXK, NAP

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	313	—	P15121

Ligands and binding sites

NXK · 2-(2-((3-boronobenzyl)carbamoyl)-5-fluorophenoxy)acetic acid · ligand · chains A
NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6TUC · Human Aldose Reductase in complex with ALR25 · the same entry in another collection · chain A against A, TM-score 1.00
P15121 · AlphaFold monomer V2.0 prediction for aldo-keto reductase family 1 member B1 (P15121) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15121
Elsewhere: RCSB PDB 6TUC · PDBe 6TUC · UniProt P15121

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