MolNFT v1 · #165090 · protein

Escherichia COLI transketolase in complex with cofactor analog 2'- methoxythiamine and substrate xylulose 5-phosphate

6TJ9: “Escherichia COLI transketolase in complex with cofactor analog 2'- methoxythiamine and substrate xylulose…”. X-ray diffraction, 4 ligands (5SP, NDQ, CA). MolNFT v1 #165090 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6TJ9
Type: protein
Length: 1,331 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P27302
Ligands: 5SP, NDQ, CA, NA

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	664	—	P27302
B	—	protein	667	—	P27302

Ligands and binding sites

5SP · 5-O-phosphono-D-xylulose · ligand · 2 copies · chains A, B
NDQ · 2-[3-[(4-azanyl-2-methoxy-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · ligand · 2 copies · chains A, B
CA · Calcium ion · metal · 2 copies · chains A, B
NA · Sodium ion · metal · 2 copies · chains A, B
EDO · 1,2-ethanediol · additive · 26 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6TJ9 · Escherichia coli transketolase in complex with cofactor analog 2'-methoxythiamine and… · the same entry in another collection · chain B against B, TM-score 1.00
P27302 · AlphaFold monomer V2.0 prediction for transketolase 1 (P27302) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27302
Elsewhere: RCSB PDB 6TJ9 · PDBe 6TJ9 · UniProt P27302

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