MolNFT v1 · #164614 · protein

Structure of the rap conjugation gene regulator of the plasmid PLS20 in apo form

6T3H · Response regulator aspartate phosphatase: “Structure of the rap conjugation gene regulator of the plasmid PLS20 in apo form”. X-ray diffraction, 11 pockets (best druggability 0.84). MolNFT v1 #164614 on GenesisL1: 3D structure…

PDB: 6T3H
Type: protein
Length: 713 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Response regulator aspartate phosphatase
UniProt: E9RIY6
Pockets: 11 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Response regulator aspartate phosphatase	protein	357	79% helix, 0% strand	E9RIY6
B	Response regulator aspartate phosphatase	protein	356	78% helix, 0% strand	E9RIY6

Pockets

11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	894	0.84	0.86	100	empty
2	396	0.63	0.78	25	empty
3	59	0.56	0.89	17	empty
4	190	0.53	0.78	32	empty
5	149	0.47	0.76	26	empty

Interfaces

1 interface between chains.

A–B · 1513 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

6T3H · Structure of the Rap conjugation gene regulator of the plasmid pLS20 in apo form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E9RIY6
Elsewhere: RCSB PDB 6T3H · PDBe 6T3H · UniProt E9RIY6

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