MolNFT v1 · #164305 · protein
Taurine ABC transporter substrate binding protein taua from E. COLI in complex with taurine
6STL · Taurine-binding periplasmic protein: “Taurine ABC transporter substrate binding protein taua from E. COLI in complex with taurine”. X-ray diffraction, 2 ligands (TAU, IOD), 5 pockets (best druggability 0.76). MolNFT v1 #164305 on…
- PDB
- 6STL
- Type
- protein
- Length
- 595 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Taurine-binding periplasmic protein
- UniProt
- Q47537
- Ligands
- TAU, IOD
- Pockets
- 5 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Taurine-binding periplasmic protein | protein | 298 | 49% helix, 19% strand | Q47537 |
| B | Taurine-binding periplasmic protein | protein | 297 | 49% helix, 20% strand | Q47537 |
Ligands and binding sites
- TAU · 2-aminoethanesulfonic acid · ligand · 2 copies · chains A, B
- IOD · Iodide ion · ion · 14 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1026 | 0.76 | 0.79 | 87 | IOD |
| 2 | 105 | 0.37 | 0.75 | 32 | empty |
| 3 | 79 | 0.32 | 0.74 | 20 | empty |
| 4 | 63 | 0.32 | 0.75 | 12 | empty |
| 5 | 50 | 0.27 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 525 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6STL · Taurine ABC transporter substrate binding protein TauA from E. coli in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q47537 · AlphaFold monomer V2.0 prediction for taurine-binding periplasmic protein (Q47537) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q47537
- Elsewhere: RCSB PDB 6STL · PDBe 6STL · UniProt Q47537
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.