MolNFT v1 · #164304 · protein

Crystal structure of the cc-chemokine 5 (CCL5) E66S mutation

6STK · C-C motif chemokine 5: “Crystal structure of the cc-chemokine 5 (CCL5) E66S mutation”. X-ray diffraction. MolNFT v1 #164304 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6STK
Type: protein
Length: 129 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-C motif chemokine 5
UniProt: P13501

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C-C motif chemokine 5	protein	65	20% helix, 31% strand	P13501
B	C-C motif chemokine 5	protein	64	20% helix, 30% strand	P13501

Ligands and binding sites

ACT · Acetate ion · additive · chains A
GOL · Glycerol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 800 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

6STK · Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation · the same entry in another collection · chain A against A, TM-score 1.00
P13501 · AlphaFold monomer V2.0 prediction for C-C motif chemokine 5 (P13501) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13501
Elsewhere: RCSB PDB 6STK · PDBe 6STK · UniProt P13501

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