MolNFT v1 · #164010 · protein

Crystal structure of human kallikrein 6 (I218Y) in complex with GSK3397892A

6SKD: “Crystal structure of human kallikrein 6 (I218Y) in complex with GSK3397892A”. X-ray diffraction, 2 ligands (LH2, UNX). MolNFT v1 #164010 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6SKD
Type: protein
Length: 444 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q92876
Ligands: LH2, UNX

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	222	—	Q92876

Ligands and binding sites

LH2 · 4-[[(3~{S})-1-oxidanyl-3,4-dihydro-2,1-benzoxaborinin-3-yl]methylamino]benzenecarboximidamide · ligand · 2 copies · chains A, B
UNX · Unknown atom or ion · ion · 2 copies · chains A, B
GOL · Glycerol · additive · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6SKD · Crystal Structure of Human Kallikrein 6 (I218Y) in complex with GSK3397892A · the same entry in another collection · chain A against A, TM-score 1.00
Q92876 · AlphaFold monomer V2.0 prediction for kallikrein-6 (Q92876) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92876
Elsewhere: RCSB PDB 6SKD · PDBe 6SKD · UniProt Q92876

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