MolNFT v1 · #163815 · protein
Trypanosoma cruzi farnesyl diphosphate synthase apo structure with zinc ions
6SE2: “Trypanosoma cruzi farnesyl diphosphate synthase apo structure with zinc ions”. X-ray diffraction, 2 ligands (ZN, SO4), 2 pockets (best druggability 0.76). MolNFT v1 #163815 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6SE2
- Type
- protein
- Length
- 360 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Farnesyl diphosphate synthase
- UniProt
- Q8WS26
- Ligands
- ZN, SO4
- Pockets
- 2 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Farnesyl diphosphate synthase | protein | 360 | 74% helix, 1% strand | Q8WS26 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 797 | 0.76 | 0.80 | 62 | SO4, ZN |
| 2 | 53 | 0.32 | 0.77 | 10 | empty |
Compared structures
- 6SE2 · Trypanosoma cruzi farnesyl diphosphate synthase apo structure with zinc ions · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WS26
- Elsewhere: RCSB PDB 6SE2 · PDBe 6SE2 · UniProt Q8WS26
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.