MolNFT v1 · #163493 · protein
Crystal structure of the human organic anion transporter MFSD10 (tetran)
6S4M · Major facilitator superfamily domain-containing protein 10: “Crystal structure of the human organic anion transporter MFSD10 (tetran)”. X-ray diffraction, 2 pockets (best druggability 0.84). MolNFT v1 #163493 on GenesisL1: 3D…
- PDB
- 6S4M
- Type
- protein
- Length
- 426 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major facilitator superfamily domain-containing protein 10
- UniProt
- Q14728
- Pockets
- 2 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 84% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major facilitator superfamily domain-containing protein 10 | protein | 426 | 84% helix, 0% strand | Q14728 |
Ligands and binding sites
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 2 copies · chains A
- CIT · Citric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1093 | 0.84 | 0.85 | 68 | CIT |
| 2 | 116 | 0.59 | 0.85 | 24 | empty |
Compared structures
- 6S4M · Crystal structure of the human organic anion transporter MFSD10 (TETRAN) · the same entry in another collection · chain A against A, TM-score 1.00
- Q14728 · AlphaFold monomer V2.0 prediction for major facilitator superfamily domain-containing… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14728
- Elsewhere: RCSB PDB 6S4M · PDBe 6S4M · UniProt Q14728
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.