MolNFT v1 · #163455 · protein
Crystal structure of lipase from geobacillus stearothermophilus T6 variant E134C/F149C
6S3J: “Crystal structure of lipase from geobacillus stearothermophilus T6 variant E134C/F149C”. X-ray diffraction, 2 ligands (ZN, CA), 2 pockets (best druggability 0.58). MolNFT v1 #163455 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6S3J
- Type
- protein
- Length
- 392 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipase
- EC
- 3.1.1.3
- UniProt
- Q93A71
- Ligands
- ZN, CA
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipase (EC 3.1.1.3) | protein | 392 | 37% helix, 15% strand | Q93A71 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.58 | 0.80 | 27 | empty |
| 2 | 62 | 0.28 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6S3J · Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant E134C/F149C · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93A71
- Elsewhere: RCSB PDB 6S3J · PDBe 6S3J · UniProt Q93A71
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