MolNFT v1 · #163307 · protein
Xfel crystal structure of the human cysteinyl leukotriene receptor 1 in complex with zafirlukast
6RZ5: “Xfel crystal structure of the human cysteinyl leukotriene receptor 1 in complex with zafirlukast”. X-ray diffraction, 3 ligands (OLA, ZLK, NA). MolNFT v1 #163307 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RZ5
- Type
- protein
- Length
- 754 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y271, P0ABE7
- Ligands
- OLA, ZLK, NA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 369 | — | Q9Y271, P0ABE7 |
| B | — | protein | 385 | — | Q9Y271, P0ABE7 |
Ligands and binding sites
- OLA · Oleic acid · ligand · 19 copies · chains A, B
- ZLK · zafirlukast · ligand · 3 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 17 copies · chains A, B
- 1PE · Pentaethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RZ5 · XFEL crystal structure of the human cysteinyl leukotriene receptor 1 in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y271 · AlphaFold monomer V2.0 prediction for cysteinyl leukotriene receptor 1 (Q9Y271) · a predicted model of the same protein · chain A against A, TM-score 0.75
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain B against A, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y271
- Every structure of UniProt P0ABE7
- Elsewhere: RCSB PDB 6RZ5 · PDBe 6RZ5 · UniProt Q9Y271 · UniProt P0ABE7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.