MolNFT v1 · #163249 · protein
Trypanosoma brucei PTR1 (TBPTR1) in complex with inhibitor 4 (nmt- C0026)
6RX6: “Trypanosoma brucei PTR1 (TBPTR1) in complex with inhibitor 4 (nmt- C0026)”. X-ray diffraction, 2 ligands (NAP, KMK). MolNFT v1 #163249 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RX6
- Type
- protein
- Length
- 986 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O76290
- Ligands
- NAP, KMK
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 248 | — | O76290 |
| B, D | — | protein | 247 | — | O76290 |
| C | — | protein | 244 | — | O76290 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 4 copies · chains A, B, C, D
- KMK · methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate · ligand · 4 copies · chains A, B, C, D
- ACT · Acetate ion · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RX6 · Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 4 (NMT-C0026) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O76290
- Elsewhere: RCSB PDB 6RX6 · PDBe 6RX6 · UniProt O76290
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