MolNFT v1 · #163232 · protein + DNA
Sivrcm intasome (Q148H/G140S) in complex with bictegravir
6RWO: “Sivrcm intasome (Q148H/G140S) in complex with bictegravir”. Electron microscopy, 4 ligands (KLQ, ZN, MG). MolNFT v1 #163232 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RWO
- Type
- protein + DNA
- Length
- 2,162 residues
- Chains
- 16
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- E1ANT8
- Ligands
- KLQ, ZN, MG, CL
Structure
electron microscopy · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, I | — | protein | 270 | — | E1ANT8 |
| Q, S | — | dna | 23 | — | — |
| W, T | — | dna | 20 | — | — |
| E, M | — | protein | 47 | — | E1ANT8 |
| N, F | — | protein | 69 | — | E1ANT8 |
| L, D | — | protein | 207 | — | E1ANT8 |
| K, C | — | protein | 193 | — | E1ANT8 |
| J, B | — | protein | 252 | — | E1ANT8 |
Ligands and binding sites
- KLQ · Bictegravir · ligand · 2 copies · chains A, S, T, Q, W, I
- ZN · Zinc ion · metal · 8 copies · chains A, E, K, J, I, M, C, B
- MG · Magnesium ion · metal · 4 copies · chains A, I
- CL · Chloride ion · ion · 2 copies · chains A, I
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RWO · SIVrcm intasome (Q148H/G140S) in complex with bictegravir · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E1ANT8
- Elsewhere: RCSB PDB 6RWO · PDBe 6RWO · UniProt E1ANT8
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