MolNFT v1 · #162401 · protein
Tannerella forsythia promirolysin mutant E225A
6R7V: “Tannerella forsythia promirolysin mutant E225A”. X-ray diffraction, 2 ligands (CA, ZN), 3 pockets (best druggability 0.43). MolNFT v1 #162401 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6R7V
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mirolysin
- UniProt
- A0A0F7IPS1
- Ligands
- CA, ZN
- Pockets
- 3 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mirolysin | protein | 307 | 29% helix, 16% strand | A0A0F7IPS1 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
- ZN · Zinc ion · metal · chains A
- GOL · Glycerol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.43 | 0.79 | 16 | empty |
| 2 | 80 | 0.39 | 0.78 | 17 | empty |
| 3 | 57 | 0.28 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6R7V · Tannerella forsythia promirolysin mutant E225A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0F7IPS1
- Elsewhere: RCSB PDB 6R7V · PDBe 6R7V · UniProt A0A0F7IPS1
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