MolNFT v1 · #16215 · protein
Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity
1NSA: “Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity”. X-ray diffraction, 2 ligands (BEN, ZN), 2 pockets (best druggability 0.79). MolNFT v1 #16215 on GenesisL1: 3D structure, binding…
- PDB
- 1NSA
- Type
- protein
- Length
- 395 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Procarboxypeptidase B
- UniProt
- P09955
- Ligands
- BEN, ZN
- Pockets
- 2 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Procarboxypeptidase B | protein | 395 | 38% helix, 19% strand | P09955 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 336 | 0.79 | 0.90 | 38 | BEN |
| 2 | 210 | 0.48 | 0.75 | 29 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 1NSA · Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its… · the same entry in another collection · chain A against A, TM-score 1.00
- P09955 · AlphaFold monomer V2.0 prediction for carboxypeptidase B (P09955) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09955
- Elsewhere: RCSB PDB 1NSA · PDBe 1NSA · UniProt P09955
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