MolNFT v1 · #162124 · protein

Crystal structure of human aquaporin 7 at 2.2 a resolution

6QZJ · Aquaporin-7: “Crystal structure of human aquaporin 7 at 2.2 a resolution”. X-ray diffraction, 1 ligand (PO4), 1 pocket (best druggability 0.69). MolNFT v1 #162124 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6QZJ
Type: protein
Length: 245 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aquaporin-7
UniProt: O14520
Ligands: PO4
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aquaporin-7	protein	245	71% helix, 0% strand	O14520

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A
GOL · Glycerol · additive · 11 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	443	0.69	0.80	57	GOL

Compared structures

6QZJ · Crystal structure of human Aquaporin 7 at 2.2 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
O14520 · AlphaFold monomer V2.0 prediction for aquaporin-7 (O14520) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14520
Elsewhere: RCSB PDB 6QZJ · PDBe 6QZJ · UniProt O14520

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