UniProt O14520
Aquaporin-7 (O14520)
Aquaporin-7 (UniProt O14520): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 86 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14520
- Protein
- Aquaporin-7
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 86 · 7 records with a druggable one
Structures
12 records of O14520 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KXW | Crystal structure of human aquaporin AQP7 in bound to glycerol | x-ray diffraction | A, B, C, D | — | 12 (best 0.85) |
| 6KXW | Crystal structure of human aquaporin AQP7 in bound to glycerol | x-ray diffraction | A, B, C, D | — | — |
| 6N1G | Crystal structure of Aquaglyceroporin AQP7 | x-ray diffraction | A, C, B, D | — | 12 (best 0.73) |
| 6N1G | Crystal structure of aquaglyceroporin AQP7 | x-ray diffraction | A, C, B, D | — | — |
| 6QZI | Crystal structure of human Aquaporin 7 at 1.9 A resolution | x-ray diffraction | A | PO4 | 1 (best 0.70) |
| 6QZI | Crystal structure of human aquaporin 7 at 1.9 a resolution | x-ray diffraction | A | PO4 | — |
| 6QZJ | Crystal structure of human Aquaporin 7 at 2.2 A resolution | x-ray diffraction | A | PO4 | 1 (best 0.69) |
| 6QZJ | Crystal structure of human aquaporin 7 at 2.2 a resolution | x-ray diffraction | A | PO4 | — |
| 8AMW | AQP7 dimer of tetramers_C1 | electron microscopy | A, B, C, D, E, F, G, H | — | 20 (best 0.87) |
| 8AMX | AQP7 dimer of tetramers_D4 | electron microscopy | A, B, C, D, E, F, G, H | — | 20 (best 0.87) |
| 8C9H | AQP7_inhibitor | electron microscopy | A, B, C, D, E, F, G, H | T60 | 20 (best 0.87) |
| O14520 | AlphaFold monomer V2.0 prediction for aquaporin-7 (O14520) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6QZJ chain A against the predicted model O14520: TM-score 1.00, RMSD 0.42 Å
- 6QZJ chain A against the predicted model O14520: TM-score 1.00, RMSD 0.42 Å
- 6QZI chain A against the predicted model O14520: TM-score 0.99, RMSD 0.50 Å
- 6QZI chain A against the predicted model O14520: TM-score 0.99, RMSD 0.50 Å
- 8AMX chain G against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
- 8AMX chain F against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
- 8AMX chain D against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
- 8AMX chain B against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
- 8AMX chain C against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
- 8AMX chain H against the predicted model O14520: TM-score 0.99, RMSD 0.60 Å
Elsewhere
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