MolNFT v1 · #16163 · protein

Structure of avm-W110K (W110K mutant of avidin)

1NQN: “Structure of avm-W110K (W110K mutant of avidin)”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #16163 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1NQN
Type: protein
Length: 229 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Avidin
UniProt: P02701
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Avidin	protein	118	5% helix, 53% strand	P02701
B	Avidin	protein	111	5% helix, 53% strand	P02701

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.37	0.75	15	empty

Interfaces

1 interface between chains.

A–B · 1931 Å² buried · 37 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1NQN · Structure of Avm-W110K (W110K mutant of avidin) · the same entry in another collection · chain A against A, TM-score 1.00
P02701 · AlphaFold monomer V2.0 prediction for avidin (P02701) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02701
Elsewhere: RCSB PDB 1NQN · PDBe 1NQN · UniProt P02701

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