MolNFT v1 · #161254 · protein
Nterminal domain of human SMU1 in complex with LSP641
6Q8J · WD40 repeat-containing protein SMU1: “Nterminal domain of human SMU1 in complex with LSP641”. X-ray diffraction, 1 ligand (XS4). MolNFT v1 #161254 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Q8J
- Type
- protein
- Length
- 188 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- WD40 repeat-containing protein SMU1
- UniProt
- Q2TAY7
- Ligands
- XS4
Structure
x-ray diffraction · 1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | WD40 repeat-containing protein SMU1 | protein | 188 | 66% helix, 1% strand | Q2TAY7 |
Ligands and binding sites
- XS4 · 1-~{tert}-butyl-3-[6-(3,5-dimethoxyphenyl)-2-[[1-[1-(phenylmethyl)piperidin-4-yl]-1,2,3-triazol-4-yl]methylamino]pyrido[2,3-d]pyrimidin-7-yl]urea · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6Q8J · Nterminal domain of human SMU1 in complex with LSP641 · the same entry in another collection · chain A against A, TM-score 1.00
- Q2TAY7 · AlphaFold monomer V2.0 prediction for WD40 repeat-containing protein SMU1 (Q2TAY7) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2TAY7
- Elsewhere: RCSB PDB 6Q8J · PDBe 6Q8J · UniProt Q2TAY7
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