MolNFT v1 · #161199 · protein
Crystal structure of C39S mutant of thioredoxin H1 from chlamydomonas reinhardtii
6Q6U · Thioredoxin H-type: “Crystal structure of C39S mutant of thioredoxin H1 from chlamydomonas reinhardtii”. X-ray diffraction, 1 pocket (best druggability 0.35). MolNFT v1 #161199 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6Q6U
- Type
- protein
- Length
- 221 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thioredoxin H-type
- UniProt
- P80028
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin H-type | protein | 111 | 44% helix, 26% strand | P80028 |
| B | Thioredoxin H-type | protein | 110 | 44% helix, 26% strand | P80028 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.35 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 606 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 6Q6U · Crystal structure of C39S mutant of thioredoxin h1 from Chlamydomonas reinhardtii · the same entry in another collection · chain A against A, TM-score 1.00
- P80028 · AlphaFold monomer V2.0 prediction for thioredoxin H-type (P80028) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P80028
- Elsewhere: RCSB PDB 6Q6U · PDBe 6Q6U · UniProt P80028
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