MolNFT v1 · #160849 · protein
X-ray crystal structure of C. elegans stim ef-SAM domain
6PW7 · Stromal interaction molecule 1: “X-ray crystal structure of C. elegans stim ef-SAM domain”. X-ray diffraction, 1 ligand (CA), 6 pockets (best druggability 0.43). MolNFT v1 #160849 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6PW7
- Type
- protein
- Length
- 322 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Stromal interaction molecule 1
- UniProt
- G5EF60
- Ligands
- CA
- Pockets
- 6 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Stromal interaction molecule 1 | protein | 161 | 68% helix, 4% strand | G5EF60 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 114 | 0.43 | 0.77 | 20 | empty |
| 2 | 61 | 0.37 | 0.79 | 18 | empty |
| 3 | 61 | 0.36 | 0.78 | 15 | empty |
| 4 | 82 | 0.35 | 0.75 | 16 | empty |
| 5 | 63 | 0.32 | 0.75 | 9 | empty |
Interfaces
1 interface between chains.
- A–B · 219 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G5EF60
- Elsewhere: RCSB PDB 6PW7 · PDBe 6PW7 · UniProt G5EF60
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