GL1X · GenesisL1 explorer

MolNFT v1 · #160845 · protein

LARP1 DM15 fyre (F844Y, R847E) mutant bound to M7GPPPG dinucleotide (capg)

6PW3: “LARP1 DM15 fyre (F844Y, R847E) mutant bound to M7GPPPG dinucleotide (capg)”. X-ray diffraction, 2 ligands (GTG, MG). MolNFT v1 #160845 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6PW3
Type
protein
Length
576 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q6PKG0
Ligands
GTG, MG

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
C—protein149—Q6PKG0
A—protein144—Q6PKG0
B—protein140—Q6PKG0
D—protein143—Q6PKG0

Ligands and binding sites

  • GTG · 7-methyl-guanosine-5'-triphosphate-5'-guanosine · ligand · 2 copies · chains C, B
  • MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6PW3 · LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG) · the same entry in another collection · chain D against D, TM-score 1.00
  • Q6PKG0 · AlphaFold monomer V2.0 prediction for la-related protein 1 (Q6PKG0) · a predicted model of the same protein · chain B against A, TM-score 0.99

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