MolNFT v1 · #160350 · protein

Spaga wild type apo structure

6PHU · Alpha-galactosidase: “Spaga wild type apo structure”. X-ray diffraction, 7 pockets (best druggability 0.46). MolNFT v1 #160350 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6PHU
Type: protein
Length: 722 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-galactosidase
EC: 3.2.1.22
UniProt: A0A0H2URQ6
Pockets: 7 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-galactosidase (EC 3.2.1.22)	protein	722	21% helix, 33% strand	A0A0H2URQ6

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 2 copies · chains A
TLA · L(+)-tartaric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	111	0.46	0.79	30	empty
2	115	0.44	0.77	21	EDO
3	109	0.39	0.75	23	empty
4	66	0.36	0.78	15	EDO
5	81	0.32	0.73	16	empty

Compared structures

6PHU · SpAga wild type apo structure · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0H2URQ6
Elsewhere: RCSB PDB 6PHU · PDBe 6PHU · UniProt A0A0H2URQ6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.