MolNFT v1 · #160319 · protein

Mtsl labelled T4 lysozyme pseudo-wild type K65C mutant

6PGY · Endolysin: “Mtsl labelled T4 lysozyme pseudo-wild type K65C mutant”. X-ray diffraction, 2 ligands (MTN, CL), 1 pocket (best druggability 0.52). MolNFT v1 #160319 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6PGY
Type: protein
Length: 162 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endolysin
EC: 3.2.1.17
UniProt: D9IEF7
Ligands: MTN, CL
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endolysin (EC 3.2.1.17)	protein	162	66% helix, 9% strand	D9IEF7

Ligands and binding sites

MTN · S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate · ligand · chains A
CL · Chloride ion · ion · 2 copies · chains A
HED · 2-hydroxyethyl disulfide · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.52	0.75	31	empty

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

6PGY · MTSL labelled T4 lysozyme pseudo-wild type K65C mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D9IEF7
Elsewhere: RCSB PDB 6PGY · PDBe 6PGY · UniProt D9IEF7

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