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MolNFT v1 · #159807 · protein + DNA

Post-catalytic nicked complex of human DNA polymerase mu with 1-nt gapped substrate containing template 8OG and newly incorporated damp

6P1O: “Post-catalytic nicked complex of human DNA polymerase mu with 1-nt gapped substrate containing template 8OG…”. X-ray diffraction, 6 ligands (PPV, ATP, MN). MolNFT v1 #159807 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
6P1O
Type
protein + DNA
Length
344 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9NP87
Ligands
PPV, ATP, MN, MG, NA, CL

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein326—Q9NP87
T—dna9——
P—dna5——
D—dna4——

Ligands and binding sites

  • PPV · Pyrophosphate · ligand · chains A, P
  • ATP · Adenosine-5'-triphosphate · ligand · chains A, P
  • MN · Manganese (II) ion · metal · chains A, P
  • MG · Magnesium ion · metal · chains A, P
  • NA · Sodium ion · metal · chains A, P
  • CL · Chloride ion · ion · 3 copies · chains A, T
  • EDO · 1,2-ethanediol · additive · chains A, P
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6P1O · Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NP87 · AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9NP87) · a predicted model of the same protein · chain A against A, TM-score 0.99

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