MolNFT v1 · #159786 · protein
Structure of spastin aaa domain (wild-type) in complex with diaminotriazole-based inhibitor
6P12: “Structure of spastin aaa domain (wild-type) in complex with diaminotriazole-based inhibitor”. X-ray diffraction, 2 ligands (NKY, SO4). MolNFT v1 #159786 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6P12
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8I0P1
- Ligands
- NKY, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 281 | — | Q8I0P1 |
Ligands and binding sites
- NKY · 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide · ligand · chains B
- SO4 · Sulfate ion · ion · chains B
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6P12 · Structure of spastin AAA domain (wild-type) in complex with diaminotriazole-based… · the same entry in another collection · chain B against B, TM-score 1.00
- Q8I0P1 · AlphaFold monomer V2.0 prediction for spastin (Q8I0P1) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8I0P1
- Elsewhere: RCSB PDB 6P12 · PDBe 6P12 · UniProt Q8I0P1
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