MolNFT v1 · #159576 · protein + DNA
Structure of HIV-1 reverse transcriptase (rt) in complex with dsdna and (+)ftc-tp
6OTZ: “Structure of HIV-1 reverse transcriptase (rt) in complex with dsdna and (+)ftc-tp”. X-ray diffraction, 3 ligands (N8G, MG, SO4). MolNFT v1 #159576 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6OTZ
- Type
- protein + DNA
- Length
- 998 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P04585
- Ligands
- N8G, MG, SO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 554 | — | P04585 |
| B | — | protein | 403 | — | P04585 |
| P | — | dna | 18 | — | — |
| T | — | dna | 23 | — | — |
Ligands and binding sites
- N8G · [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate · ligand · chains A, P, T
- MG · Magnesium ion · metal · 2 copies · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A, B, P, T
- GOL · Glycerol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6OTZ · Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (+)FTC-TP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04585
- Elsewhere: RCSB PDB 6OTZ · PDBe 6OTZ · UniProt P04585
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