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Ligand · N8G

N8G · [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

N8G, [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (C8 H13 F N3 O12 P3 S, 487.2 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component
N8G
Formula
C8 H13 F N3 O12 P3 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

N8G in 3 structures; the first of them:

  • 6OTZ · Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (+)FTC-TP · N8G A604 · binds LYS65, ARG72, ASP110, VAL111, GLY112, ASP113, ALA114, TYR115 and 7 more
  • 6OTZ · Structure of HIV-1 reverse transcriptase (rt) in complex with dsdna and (+)ftc-tp · N8G A604 · binds LYS65, ARG72, ASP110, VAL111, GLY112, ASP113, ALA114, TYR115 and 6 more
  • 6UJZ · HIV-1 wild-type reverse transcriptase-DNA complex with (+)-ftc-tp · N8G A604 · binds LYS65, LYS70, ARG72, ASP110, VAL111, GLY112, ASP113, ALA114 and 7 more

Residues it binds most

ASP 3, LYS 3, DG 3, ALA 3, ARG 3, GLN 3, GLY 3, TYR 3, VAL 3, DC 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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