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MolNFT v1 · #159411 · protein

Structural elucidation of the ectodomain of mouse UNC5H2

6OOL · Netrin receptor UNC5B: “Structural elucidation of the ectodomain of mouse UNC5H2”. X-ray diffraction, 4 ligands (NAG, MAN, FUC). MolNFT v1 #159411 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6OOL
Type
protein
Length
244 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Netrin receptor UNC5B
UniProt
Q8K1S3
Ligands
NAG, MAN, FUC, CL

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 46% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANetrin receptor UNC5Bprotein2442% helix, 46% strandQ8K1S3

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
  • MAN · alpha-D-mannopyranose · sugar · 2 copies · chains A
  • FUC · alpha-L-fucopyranose · sugar · chains A
  • CL · Chloride ion · ion · 13 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 5 disulfide, 3 glycan (disulfide, C-mannosylation, N-glycosylation).

Compared structures

  • 6OOL · Structural elucidation of the Ectodomain of mouse UNC5H2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8K1S3 · AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8K1S3) · a predicted model of the same protein · chain A against A, TM-score 0.70

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