UniProt Q8K1S3
netrin receptor Unc5h2 (Q8K1S3)
netrin receptor Unc5h2 (UniProt Q8K1S3): 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8K1S3
- Protein
- netrin receptor Unc5h2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 8 · 1 record with a druggable one
Structures
5 records of Q8K1S3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WMG | Crystal structure of the UNC5H2 death domain | x-ray diffraction | A, B, C, D, E, F | SO3, SO4 | — |
| 1WMG | Crystal structure of the UNC5H2 death domain | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6OOL | Structural elucidation of the Ectodomain of mouse UNC5H2 | x-ray diffraction | A | NAG, FUC, MAN, CL | — |
| 6OOL | Structural elucidation of the ectodomain of mouse UNC5H2 | x-ray diffraction | A | NAG, FUC, MAN, CL | — |
| Q8K1S3 | AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8K1S3) | predicted | A | — | 8 (best 0.78) |
Ligands
Experiment against prediction
- 1WMG chain F against the predicted model Q8K1S3: TM-score 0.89, RMSD 1.59 Å
- 1WMG chain F against the predicted model Q8K1S3: TM-score 0.89, RMSD 1.59 Å
- 1WMG chain E against the predicted model Q8K1S3: TM-score 0.88, RMSD 1.65 Å
- 1WMG chain E against the predicted model Q8K1S3: TM-score 0.88, RMSD 1.65 Å
- 1WMG chain C against the predicted model Q8K1S3: TM-score 0.88, RMSD 1.74 Å
- 1WMG chain C against the predicted model Q8K1S3: TM-score 0.88, RMSD 1.74 Å
- 1WMG chain B against the predicted model Q8K1S3: TM-score 0.87, RMSD 1.57 Å
- 1WMG chain B against the predicted model Q8K1S3: TM-score 0.87, RMSD 1.57 Å
- 1WMG chain D against the predicted model Q8K1S3: TM-score 0.85, RMSD 2.06 Å
- 1WMG chain D against the predicted model Q8K1S3: TM-score 0.85, RMSD 2.06 Å
Elsewhere
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