MolNFT v1 · #159287 · protein + RNA

Cryo-EM structure of the plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

6OKK: “Cryo-EM structure of the plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small…”. Electron microscopy, 3 ligands (34G, MG, ZN). MolNFT v1 #159287 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6OKK
Type: protein + RNA
Length: 5,788 residues
Chains: 33
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O97313, Q8IJD4, Q8IKH8, Q8I3R0, Q8IIU8, Q8IL02, Q8IDR9, Q8IBN5, Q8IET7, O77395, Q8IM10, A0A0L7M7C8, Q8IK02, Q8IBQ5, Q8I3U6, O97248, O97249, Q8IIA2, C0H4K8, Q8IDB0, O77381, Q8I502, C0H5C2, Q8IFP2, Q8IHS5, Q8I3R6, Q8ILN8, O96258, Q8IEN2, Q8IKL9, O96269
Ligands: 34G, MG, ZN

Structure

electron microscopy · 33 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	rna	1608	—	—
B	—	protein	210	—	O97313
C	—	protein	195	—	Q8IJD4
D	—	protein	157	—	Q8IKH8
E	—	protein	185	—	Q8I3R0
F	—	protein	257	—	Q8IIU8
G	—	protein	224	—	Q8IL02
H	—	protein	204	—	Q8IDR9
I	—	protein	180	—	Q8IBN5
J	—	protein	188	—	Q8IET7
K	—	protein	129	—	O77395
L	—	protein	172	—	Q8IM10
M	—	protein	138	—	A0A0L7M7C8
N	—	protein	98	—	Q8IK02
O	—	protein	79	—	Q8IBQ5
P	—	protein	127	—	Q8I3U6
Q	—	protein	144	—	O97248
R	—	protein	98	—	O97249
S	—	protein	128	—	Q8IIA2
T	—	protein	48	—	C0H4K8
U	—	protein	149	—	Q8IDB0
V	—	protein	146	—	O77381
W	—	protein	95	—	Q8I502
X	—	protein	96	—	C0H5C2
Y	—	protein	154	—	Q8IFP2
Z	—	protein	72	—	Q8IHS5
a	—	protein	120	—	Q8I3R6
b	—	protein	41	—	Q8ILN8
c	—	protein	95	—	O96258
d	—	protein	76	—	Q8IEN2
e	—	protein	58	—	Q8IKL9
f	—	protein	43	—	O96269
g	—	rna	74	—	—

Ligands and binding sites

34G · emetine · ligand · chains A, P
MG · Magnesium ion · metal · 67 copies · chains A, c, U, M
ZN · Zinc ion · metal · chains T

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6OKK · Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan… · the same entry in another collection · chain F against F, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O97313
Every structure of UniProt Q8IJD4
Every structure of UniProt Q8IKH8
Every structure of UniProt Q8I3R0
Every structure of UniProt Q8IIU8
Every structure of UniProt Q8IL02
Every structure of UniProt Q8IDR9
Every structure of UniProt Q8IBN5
Every structure of UniProt Q8IET7
Every structure of UniProt O77395
Every structure of UniProt Q8IM10
Every structure of UniProt A0A0L7M7C8
Every structure of UniProt Q8IK02
Every structure of UniProt Q8IBQ5
Every structure of UniProt Q8I3U6
Every structure of UniProt O97248
Every structure of UniProt O97249
Every structure of UniProt Q8IIA2
Every structure of UniProt C0H4K8
Every structure of UniProt Q8IDB0
Every structure of UniProt O77381
Every structure of UniProt Q8I502
Every structure of UniProt C0H5C2
Every structure of UniProt Q8IFP2
Every structure of UniProt Q8IHS5
Every structure of UniProt Q8I3R6
Every structure of UniProt Q8ILN8
Every structure of UniProt O96258
Every structure of UniProt Q8IEN2
Every structure of UniProt Q8IKL9
Every structure of UniProt O96269
Elsewhere: RCSB PDB 6OKK · PDBe 6OKK · UniProt O97313 · UniProt Q8IJD4 · UniProt Q8IKH8 · UniProt Q8I3R0 · UniProt Q8IIU8 · UniProt Q8IL02 · UniProt Q8IDR9 · UniProt Q8IBN5 · UniProt Q8IET7 · UniProt O77395 · UniProt Q8IM10 · UniProt A0A0L7M7C8 · UniProt Q8IK02 · UniProt Q8IBQ5 · UniProt Q8I3U6 · UniProt O97248 · UniProt O97249 · UniProt Q8IIA2 · UniProt C0H4K8 · UniProt Q8IDB0 · UniProt O77381 · UniProt Q8I502 · UniProt C0H5C2 · UniProt Q8IFP2 · UniProt Q8IHS5 · UniProt Q8I3R6 · UniProt Q8ILN8 · UniProt O96258 · UniProt Q8IEN2 · UniProt Q8IKL9 · UniProt O96269

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