Research workbench
Cryo-EM structure of the plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Analyse Cryo-EM structure of the plasmodium falciparum 80S ribosome bound to the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6OKK
- Type
- protein + RNA
- Length
- 5,788 residues
- Chains
- 33
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O97313, Q8IJD4, Q8IKH8, Q8I3R0, Q8IIU8, Q8IL02, Q8IDR9, Q8IBN5, Q8IET7, O77395, Q8IM10, A0A0L7M7C8, Q8IK02, Q8IBQ5, Q8I3U6, O97248, O97249, Q8IIA2, C0H4K8, Q8IDB0, O77381, Q8I502, C0H5C2, Q8IFP2, Q8IHS5, Q8I3R6, Q8ILN8, O96258, Q8IEN2, Q8IKL9, O96269
- Ligands
- 34G, MG, ZN
Structure
electron microscopy · 33 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | rna | 1608 | — | — |
| B | — | protein | 210 | — | O97313 |
| C | — | protein | 195 | — | Q8IJD4 |
| D | — | protein | 157 | — | Q8IKH8 |
| E | — | protein | 185 | — | Q8I3R0 |
| F | — | protein | 257 | — | Q8IIU8 |
| G | — | protein | 224 | — | Q8IL02 |
| H | — | protein | 204 | — | Q8IDR9 |
| I | — | protein | 180 | — | Q8IBN5 |
| J | — | protein | 188 | — | Q8IET7 |
| K | — | protein | 129 | — | O77395 |
| L | — | protein | 172 | — | Q8IM10 |
| M | — | protein | 138 | — | A0A0L7M7C8 |
| N | — | protein | 98 | — | Q8IK02 |
| O | — | protein | 79 | — | Q8IBQ5 |
| P | — | protein | 127 | — | Q8I3U6 |
| Q | — | protein | 144 | — | O97248 |
| R | — | protein | 98 | — | O97249 |
| S | — | protein | 128 | — | Q8IIA2 |
| T | — | protein | 48 | — | C0H4K8 |
| U | — | protein | 149 | — | Q8IDB0 |
| V | — | protein | 146 | — | O77381 |
| W | — | protein | 95 | — | Q8I502 |
| X | — | protein | 96 | — | C0H5C2 |
| Y | — | protein | 154 | — | Q8IFP2 |
| Z | — | protein | 72 | — | Q8IHS5 |
| a | — | protein | 120 | — | Q8I3R6 |
| b | — | protein | 41 | — | Q8ILN8 |
| c | — | protein | 95 | — | O96258 |
| d | — | protein | 76 | — | Q8IEN2 |
| e | — | protein | 58 | — | Q8IKL9 |
| f | — | protein | 43 | — | O96269 |
| g | — | rna | 74 | — | — |
Ligands and binding sites
- 34G · emetine · ligand · chains A, P
- MG · Magnesium ion · metal · 67 copies · chains A, c, U, M
- ZN · Zinc ion · metal · chains T
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6OKK · Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan… · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O97313
- Every structure of UniProt Q8IJD4
- Every structure of UniProt Q8IKH8
- Every structure of UniProt Q8I3R0
- Every structure of UniProt Q8IIU8
- Every structure of UniProt Q8IL02
- Every structure of UniProt Q8IDR9
- Every structure of UniProt Q8IBN5
- Every structure of UniProt Q8IET7
- Every structure of UniProt O77395
- Every structure of UniProt Q8IM10
- Every structure of UniProt A0A0L7M7C8
- Every structure of UniProt Q8IK02
- Every structure of UniProt Q8IBQ5
- Every structure of UniProt Q8I3U6
- Every structure of UniProt O97248
- Every structure of UniProt O97249
- Every structure of UniProt Q8IIA2
- Every structure of UniProt C0H4K8
- Every structure of UniProt Q8IDB0
- Every structure of UniProt O77381
- Every structure of UniProt Q8I502
- Every structure of UniProt C0H5C2
- Every structure of UniProt Q8IFP2
- Every structure of UniProt Q8IHS5
- Every structure of UniProt Q8I3R6
- Every structure of UniProt Q8ILN8
- Every structure of UniProt O96258
- Every structure of UniProt Q8IEN2
- Every structure of UniProt Q8IKL9
- Every structure of UniProt O96269
- Elsewhere: RCSB PDB 6OKK · PDBe 6OKK · UniProt O97313 · UniProt Q8IJD4 · UniProt Q8IKH8 · UniProt Q8I3R0 · UniProt Q8IIU8 · UniProt Q8IL02 · UniProt Q8IDR9 · UniProt Q8IBN5 · UniProt Q8IET7 · UniProt O77395 · UniProt Q8IM10 · UniProt A0A0L7M7C8 · UniProt Q8IK02 · UniProt Q8IBQ5 · UniProt Q8I3U6 · UniProt O97248 · UniProt O97249 · UniProt Q8IIA2 · UniProt C0H4K8 · UniProt Q8IDB0 · UniProt O77381 · UniProt Q8I502 · UniProt C0H5C2 · UniProt Q8IFP2 · UniProt Q8IHS5 · UniProt Q8I3R6 · UniProt Q8ILN8 · UniProt O96258 · UniProt Q8IEN2 · UniProt Q8IKL9 · UniProt O96269
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