MolNFT v1 · #159135 · protein

Structure of salmonella type III secretion system needle filament

6OFH · Protein prgi: “Structure of salmonella type III secretion system needle filament”. Electron microscopy, 20 pockets (best druggability 0.60). MolNFT v1 #159135 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6OFH
Type: protein
Length: 1,482 residues
Chains: 19
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein prgi
UniProt: A0A0H3NF82
Pockets: 20 · best druggability 0.60

Structure

electron microscopy · 1 distinct chain · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
D, U, V, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T	Protein prgi	protein	78	77% helix, 0% strand	A0A0H3NF82

Pockets

20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	494	0.60	0.74	49	empty
2	325	0.56	0.76	38	empty
3	332	0.55	0.75	40	empty
4	221	0.53	0.77	39	empty
5	215	0.51	0.76	20	empty

Interfaces

53 interfaces between chains.

V–J · 918 Å² buried · 12 hydrogen bonds · protein-protein
G–M · 909 Å² buried · 14 hydrogen bonds · protein-protein
I–O · 906 Å² buried · 12 hydrogen bonds · protein-protein
H–N · 904 Å² buried · 15 hydrogen bonds · protein-protein
L–R · 899 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

6OFH · Structure of Salmonella type III secretion system needle filament · the same entry in another collection · chain D against D, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0H3NF82
Elsewhere: RCSB PDB 6OFH · PDBe 6OFH · UniProt A0A0H3NF82

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