MolNFT v1 · #159130 · protein

Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with sulfonamide derivative 1, pyrophosphate, and glutamine

6OFC: “Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with sulfonamide…”. X-ray diffraction, 3 ligands (SFH, POP, CL). MolNFT v1 #159130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6OFC
Type: protein
Length: 2,658 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P9WJJ2
Ligands: SFH, POP, CL

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	660	—	P9WJJ2
B	—	protein	670	—	P9WJJ2
C	—	protein	666	—	P9WJJ2
D	—	protein	662	—	P9WJJ2

Ligands and binding sites

SFH · 5'-O-[(pyridine-3-carbonyl)sulfamoyl]adenosine · ligand · 8 copies · chains A, D, B, C
POP · Pyrophosphate 2- · ligand · chains B
CL · Chloride ion · ion · 4 copies · chains A, B, D
GOL · Glycerol · additive · 2 copies · chains A, B, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6OFC · Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
P9WJJ2 · AlphaFold monomer V2.0 prediction for glutamine-dependent NAD(+) synthetase (P9WJJ2) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P9WJJ2
Elsewhere: RCSB PDB 6OFC · PDBe 6OFC · UniProt P9WJJ2

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