MolNFT v1 · #159000 · protein
Human equilibrative nucleoside transporter-1, dilazep bound
6OB7 · Equilibrative nucleoside transporter 1: “Human equilibrative nucleoside transporter-1, dilazep bound”. X-ray diffraction, 1 ligand (8DZ), 1 pocket (best druggability 0.80). MolNFT v1 #159000 on GenesisL1: 3D structure, binding sites…
- PDB
- 6OB7
- Type
- protein
- Length
- 381 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Equilibrative nucleoside transporter 1
- UniProt
- Q99808
- Ligands
- 8DZ
- Pockets
- 1 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 80% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Equilibrative nucleoside transporter 1 | protein | 381 | 80% helix, 1% strand | Q99808 |
Ligands and binding sites
- 8DZ · (1,4-diazepane-1,4-diyl)di(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate) · ligand · chains A
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 18 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 719 | 0.80 | 0.84 | 70 | OLC, 8DZ |
Compared structures
- 6OB7 · Human equilibrative nucleoside transporter-1, dilazep bound · the same entry in another collection · chain A against A, TM-score 1.00
- Q99808 · AlphaFold monomer V2.0 prediction for equilibrative nucleoside transporter 1 (Q99808) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99808
- Elsewhere: RCSB PDB 6OB7 · PDBe 6OB7 · UniProt Q99808
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