MolNFT v1 · #418873 · protein
AlphaFold monomer V2.0 prediction for equilibrative nucleoside transporter 1 (Q99808)
Q99808: “AlphaFold monomer V2.0 prediction for equilibrative nucleoside transporter 1 (Q99808)”. 4 pockets (best druggability 0.82). MolNFT v1 #418873 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q99808
- Type
- protein
- Length
- 456 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Equilibrative nucleoside transporter 1
- UniProt
- Q99808
- Pockets
- 4 · best druggability 0.82
Structure
1 distinct chain · 75% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Equilibrative nucleoside transporter 1 | protein | 456 | 75% helix, 1% strand | Q99808 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 722 | 0.82 | 0.85 | 71 | empty |
| 2 | 166 | 0.51 | 0.78 | 29 | empty |
| 3 | 65 | 0.31 | 0.75 | 15 | empty |
| 4 | 67 | 0.28 | 0.73 | 13 | empty |
Compared structures
- 8TZI · Human equilibrative nucleoside transporter-1, JH-ENT-01 bound · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 6OB7 · Human equilibrative nucleoside transporter-1, dilazep bound · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 6OB7 · Human equilibrative nucleoside transporter-1, dilazep bound · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 6OB6 · Human equilibrative nucleoside transporter-1, S-(4-nitrobenzyl)-6-thioinosine bound… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 6OB6 · Human equilibrative nucleoside transporter-1, S-(4-nitrobenzyl)-6- thioinosine bound… · an experimental structure of the same protein · chain A against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99808
- Elsewhere: UniProt Q99808 · AlphaFold DB Q99808
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