GL1X · GenesisL1 explorer

MolNFT v1 · #158721 · protein

Drosophila melanogaster cenp-C cupin domain

6O2K · Centromeric protein-C, isoform a: “Drosophila melanogaster cenp-C cupin domain”. X-ray diffraction, 1 pocket (best druggability 0.76). MolNFT v1 #158721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6O2K
Type
protein
Length
275 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Centromeric protein-C, isoform a
UniProt
Q9VHP9
Pockets
1 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 13% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACentromeric protein-C, isoform aprotein13312% helix, 43% strandQ9VHP9
BCentromeric protein-C, isoform aprotein14215% helix, 42% strandQ9VHP9

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12140.760.9135empty

Interfaces

1 interface between chains.

  • A–B · 1965 Ų buried · 29 hydrogen bonds · protein-protein

Compared structures

  • 6O2K · Drosophila melanogaster CENP-C cupin domain · the same entry in another collection · chain A against A, TM-score 1.00

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