MolNFT v1 · #158697 · protein

Structure of human plasma kallikrein protease domain with inhibitor

6O1S: “Structure of human plasma kallikrein protease domain with inhibitor”. X-ray diffraction, 2 ligands (7SD, PO4). MolNFT v1 #158697 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6O1S
Type: protein
Length: 239 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P03952
Ligands: 7SD, PO4

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
E	—	protein	239	—	P03952

Ligands and binding sites

7SD · N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-1-({4-[(1H-pyrazol-1-yl)methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide · ligand · chains E
PO4 · Phosphate ion · ion · chains E
EDO · 1,2-ethanediol · additive · chains E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6O1S · Structure of human plasma kallikrein protease domain with inhibitor · the same entry in another collection · chain E against E, TM-score 1.00
P03952 · AlphaFold monomer V2.0 prediction for plasma kallikrein (P03952) · a predicted model of the same protein · chain E against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03952
Elsewhere: RCSB PDB 6O1S · PDBe 6O1S · UniProt P03952

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